Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 3/20 | 0.32 |
| ▸ | GABRD | O14764 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.32 |
| ▸ | GABRE | P78334 | 3/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957944 | 0.89 | CCR1 (0.37) | MEN1KMT2ACCR1CCR2GABRP | |
| SCHEMBL2962285 | 0.88 | MEN1 (0.41) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL13201703 | 0.87 | GABRP (0.34) | MEN1KMT2ACCR1CCR2GABRP | |
| SCHEMBL27168510 | 0.86 | GABRP (0.35) | MEN1KMT2ACCR1CCR2GABRP | |
| SCHEMBL1531236 | 0.84 | KMT2A (0.34) | KMT2ACCR1CCR2GABRPGABRD | |
| SCHEMBL38481 | 0.81 | NPSR1 (0.37) | MEN1KMT2ACCR1CCR2GABRP | |
| SCHEMBL13201705 | 0.79 | MAPT (0.37) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL1531087 | 0.78 | MAPT (0.38) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL1531202 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2ACCR1CCR2GABRP | |
| SCHEMBL1531154 | 0.77 | LMNA (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767827-B2 | Pyrazole-1-carboxylate derivatives, process for the production thereof and process for the production of pyrazole derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7767827-B2 | Pyrazole-1-carboxylate derivatives, process for the production thereof and process for the production of pyrazole derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090018345-A1 | PYRAZOLE-1-CARBOXYLATE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND PROCESS FOR THE PRODUCTION OF PYRAZOLE DERIVATIVES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20090018345-A1 | PYRAZOLE-1-CARBOXYLATE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND PROCESS FOR THE PRODUCTION OF PYRAZOLE DERIVATIVES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-1884512-A1 | PYRAZOLE-1-CARBOXYLIC ESTER DERIVATIVE, METHOD FOR PRODUCING THE SAME AND METHOD FOR PRODUCING PYRAZOLE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2008-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018345-A1 | PYRAZOLE-1-CARBOXYLATE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND PROCESS FOR THE PRODUCTION OF PYRAZOLE DERIVATIVES | WEE1, CYP51A1, CYP4B1 | GPR119 1440/4885MAP2K4 3862/4885MEN1 4418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.