SCHEMBL29595013

SCHEMBL29595013

Cc1ccc(O)c(-c2nc3ccccc3[nH]2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.62
F10 P00742 2/20 0.62
PLG P00747 2/20 0.62
PLAU P00749 2/20 0.62
PRSS1 P07477 2/20 0.62
F7 P08709 1/20 0.58
ALDH1A1 P00352 8/20 0.58
NPC1 O15118 7/20 0.58
RAB9A P51151 7/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
HPGD P15428 5/20 0.58
NPSR1 Q6W5P4 3/20 0.58
HTT P42858 1/20 0.58
KDM4E B2RXH2 6/20 0.56
GAA P10253 5/20 0.56
MAPT P10636 4/20 0.56
HSD17B10 Q99714 4/20 0.56
MEN1 O00255 2/20 0.56
USP2 O75604 2/20 0.56
KMT2A Q03164 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31429745 1.00 F2 (0.62) F2F10PLGPLAUPRSS1
SCHEMBL16142437 1.00 F2 (0.62) F2F10PLGPLAUPRSS1
Benzimidazole SCHEMBL28942979 0.90 F2 (0.53) F2F10PLGPLAUPRSS1
SCHEMBL17717642 0.89 F2 (0.61) F2F10PLGPLAUPRSS1
SCHEMBL15177874 0.88 F2 (0.61) F2F10PLGPLAUPRSS1
SCHEMBL2784089 0.85 RAB9A (0.67) F7ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL31429678 0.84 GUSB (0.65) F7ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL4117255 0.84 NPC1 (0.71) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL31429655 0.82 F2 (0.62) F2F10PLGPLAUPRSS1
SCHEMBL7396100 0.82 AMY1A (0.64) F2F10PLGPLAUPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353491-B Preparation method and application of dehydroabietyl bis-benzimidazole salicylaldehyde three-ion functional fluorescent probe 南京林业大学 2023-12-29 CN claimed
CN-114539159-B Dehydroabietyl Schiff base multi-ion functional fluorescent probe and preparation method and application thereof 南京林业大学 2023-12-01 CN claimed
CN-115353491-A Preparation method and application of dehydroabietic acid based bis-benzimidazole salicylaldehyde three-ion functional fluorescent probe 南京林业大学 2022-11-18 CN claimed
CN-114539159-A Dehydroabietic acid-based Schiff base multi-ion functional fluorescent probe and preparation method and application thereof 南京林业大学 2022-05-27 CN claimed
CN-115353491-B Preparation method and application of dehydroabietyl bis-benzimidazole salicylaldehyde three-ion functional fluorescent probe 南京林业大学 2023-12-29 CN disclosed
CN-114539159-B Dehydroabietyl Schiff base multi-ion functional fluorescent probe and preparation method and application thereof 南京林业大学 2023-12-01 CN disclosed
CN-115353491-A Preparation method and application of dehydroabietic acid based bis-benzimidazole salicylaldehyde three-ion functional fluorescent probe 南京林业大学 2022-11-18 CN disclosed
CN-114539159-A Dehydroabietic acid-based Schiff base multi-ion functional fluorescent probe and preparation method and application thereof 南京林业大学 2022-05-27 CN disclosed