Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.39 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595792 | 0.79 | CYP2C9 (0.45) | MAPTLMNAPTGDR2ALDH1A1NPSR1 | |
| SCHEMBL19249693 | 0.79 | CYP2C9 (0.45) | MAPTLMNAPTGDR2ALDH1A1NPSR1 | |
| SCHEMBL20915423 | 0.77 | LOXL2 (0.75) | LOXL2DAOAOC3 | |
| SCHEMBL19249367 | 0.77 | LOXL2 (0.75) | LOXL2DAOAOC3 | |
| Hydrochloric Acid SCHEMBL20915815 | 0.76 | LOXL2 (0.76) | LOXL2DAOAOC3 | |
| Hydrochloric Acid SCHEMBL20915812 | 0.76 | LOXL2 (0.76) | LOXL2DAOAOC3 | |
| SCHEMBL19249477 | 0.75 | LOXL2 (0.61) | LOXL2PTGDR2DAOAOC3 | |
| SCHEMBL30866065 | 0.72 | P2RX4 (0.52) | MAPTHTTLMNAGAAALDH1A1 | |
| SCHEMBL29240190 | 0.72 | P2RX4 (0.52) | MAPTHTTLMNAGAAALDH1A1 | |
| SCHEMBL29595303 | 0.72 | MAPT (0.52) | MAPTHTTGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153642-B | Indole and azaindole halogenated allylamine derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2022-05-17 | — | — | CN | disclosed |