Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966612 | 1.00 | NQO2 (0.47) | NQO2MEN1ESR1GAAKMT2A | |
| SCHEMBL9740695 | 0.88 | NQO2 (0.48) | NQO2CA12CA1CA9CA2 | |
| SCHEMBL6656871 | 0.86 | NQO2 (0.43) | NQO2MEN1KMT2ALMNACA12 | |
| SCHEMBL16232221 | 0.85 | MTNR1A (0.56) | NQO2MTNR1A | |
| SCHEMBL11553716 | 0.84 | CA12 (0.40) | MEN1ESR1GAAKMT2AESR2 | |
| SCHEMBL19900028 | 0.83 | MEN1 (0.44) | MEN1ESR1GAAKMT2AESR2 | |
| SCHEMBL12676668 | 0.82 | MEN1 (0.51) | MEN1GAAKMT2APKMCYP24A1 | |
| SCHEMBL5748460 | 0.80 | LMNA (0.48) | MEN1KMT2ALMNACYP24A1CA12 | |
| SCHEMBL8209789 | 0.80 | TP53 (0.51) | MEN1KMT2ALMNAPKML3MBTL1 | |
| SCHEMBL1904847 | 0.80 | VDR (0.40) | MEN1KMT2ALMNACYP24A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218206-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2022-03-04 | — | — | CN | disclosed |