SCHEMBL29599666

SCHEMBL29599666

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)[C@@H](C)O)C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 9/20 0.70
▸ GCGR P47871 6/20 0.70
▸ C5AR1 P21730 2/20 0.70
▸ KEAP1 Q14145 1/20 0.63
▸ NPY1R P25929 1/20 0.63
▸ NPY2R P49146 1/20 0.63
▸ NPY4R P50391 1/20 0.63
▸ NPY5R Q15761 1/20 0.63
▸ CALCR P30988 3/20 0.63
▸ NMBR P28336 1/20 0.62
▸ GRPR P30550 1/20 0.62
▸ GIPR P48546 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31379433 0.94 NMBR (0.70) GLP1RGCGRC5AR1CALCRNMBR
SCHEMBL29464570 0.94 NPY2R (0.71) GLP1RNPY1RNPY2RNPY4RNPY5R
SCHEMBL31182829 0.92 GLP1R (0.73) GLP1RGCGRC5AR1KEAP1NPY1R
SCHEMBL23273229 0.92 NMBR (0.69) GLP1RGCGRC5AR1KEAP1NPY1R
SCHEMBL4956503 0.91 GLP1R (0.61) GLP1RGCGRC5AR1KEAP1NPY1R
SCHEMBL29965030 0.91 C5AR1 (0.74) GLP1RGCGRC5AR1KEAP1NPY1R
SCHEMBL29755703 0.91 GLP1R (0.72) GLP1RGCGRC5AR1KEAP1NPY1R
SCHEMBL30658246 0.90 GLP1R (0.79) GLP1RGCGRKEAP1NPY1RNPY2R
SCHEMBL30932062 0.90 GLP1R (0.74) GLP1RGCGRC5AR1KEAP1NPY1R
SCHEMBL29737187 0.90 C5AR1 (0.75) GLP1RGCGRC5AR1KEAP1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3532092-B1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2026-04-29 — — EP disclosed
US-12590131-B2 Antimicrobial peptides with alpha-core helices LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER (US) 2026-03-31 — — US disclosed
EP-3621632-B1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2025-08-13 — — EP disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 — — US disclosed
US-20250026803-A1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2025-01-23 — — US disclosed
US-12134636-B2 Immunoglobulins and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2024-11-05 — — US disclosed
US-20240279292-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2024-08-22 — — US disclosed
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation TUFTS MEDICAL CENTER (US) 2024-08-13 — — US disclosed
US-11987607-B2 Antimicrobial peptides with alpha-core helices The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (US) 2024-05-21 — — US disclosed
US-20230227516-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER 2023-07-20 — — US disclosed
CN-110101840-B Application of combination of neuropeptide B23/W23 and morphine in preparation of analgesic drugs 徐州医科大学 2023-03-28 — — CN disclosed
US-11401315-B2 Immunoglobulins and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2022-08-02 — — US disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG GLP1R 1209/4885GCGR 1242/4885C5AR1 316/4885
US-12590131-B2 Antimicrobial peptides with alpha-core helices VIP, HAMP, HM13 GLP1R 55/4885GCGR 3000/4885C5AR1 475/4885
US-11987607-B2 Antimicrobial peptides with alpha-core helices VIP, NGLY1, SPPL2B GLP1R 146/4885GCGR 2221/4885C5AR1 160/4885
US-20240279292-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES VIP, NGLY1, SPPL2B GLP1R 146/4885GCGR 2221/4885C5AR1 160/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG GLP1R 1209/4885GCGR 1242/4885C5AR1 316/4885
US-20230227516-A1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES VIP, NGLY1, SPPL2B GLP1R 146/4885GCGR 2221/4885C5AR1 160/4885
US-12060397-B2 Soluble lipidated ligand agents for treating eye inflammation LIPG, CD40, LDLR GLP1R 553/4885GCGR 648/4885C5AR1 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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