SCHEMBL29464570

SCHEMBL29464570

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)[C@@H](C)O)C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 4/20 0.71
▸ NPY4R P50391 4/20 0.71
▸ NPY5R Q15761 4/20 0.71
▸ NPY1R P25929 3/20 0.71
▸ MC4R P32245 1/20 0.68
▸ MC5R P33032 1/20 0.68
▸ MC3R P41968 1/20 0.68
▸ MC1R Q01726 1/20 0.68
▸ CXCR4 P61073 6/20 0.68
▸ GLP1R P43220 5/20 0.67
▸ CALCA P06881 1/20 0.65
▸ RAMP3 O60896 1/20 0.64
▸ CALCR P30988 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29599666 0.94 GLP1R (0.70) NPY2RNPY4RNPY5RNPY1RGLP1R
SCHEMBL29351953 0.93 NPY2R (0.74) NPY2RNPY4RNPY5RNPY1RMC4R
SCHEMBL31060386 0.91 CALCA (0.75) NPY2RNPY4RNPY5RNPY1RCXCR4
SCHEMBL29360268 0.90 NPY1R (0.74) NPY2RNPY4RNPY5RNPY1RMC4R
Acetic Acid SCHEMBL29399515 0.90 NPY1R (0.75) NPY2RNPY4RNPY5RNPY1RMC4R
SCHEMBL29355231 0.90 NPY1R (0.76) NPY2RNPY4RNPY5RNPY1RMC4R
SCHEMBL29367990 0.89 CALCA (0.69) NPY2RNPY4RNPY5RNPY1RMC4R
SCHEMBL29464565 0.89 CXCR4 (0.66) NPY2RNPY4RNPY5RNPY1RMC4R
SCHEMBL29598077 0.89 NPY2R (0.75) NPY2RNPY4RNPY5RNPY1RGLP1R
Tosactide SCHEMBL29353880 0.89 MC4R (0.77) NPY2RNPY4RNPY5RNPY1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110101840-B Application of combination of neuropeptide B23/W23 and morphine in preparation of analgesic drugs 徐州医科大学 2023-03-28 — — CN claimed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 — — US disclosed
EP-4149556-B1 PEG LIPIDOID COMPOUNDS TRANSLATE BIO INC (US) 2026-01-07 — — EP disclosed
US-12514932-B2 PEG lipidoid compounds TRANSLATE BIO, INC. (US) 2026-01-06 — — US disclosed
US-12453759-B2 Di-thioester cationic lipids TRANSLATE BIO, INC. (US) 2025-10-28 — — US disclosed
EP-4618957-A1 COMPOSITIONS COMPRISING OCTADECANEUROPEPTIDES (ODN) AND SYNTHETIC DERIVATIVES THEREOF AND METHODS OF USE FOR MODULATION OF FOOD INTAKE, OBESITY, BODY WEIGHT, NAUSEA, AND EMESIS The Trustees of The University of Pennsylvania (US) 2025-09-24 — — EP disclosed
US-20250288523-A1 PEG LIPIDOID COMPOUNDS TRANSLATE BIO INC (US) 2025-09-18 — — US disclosed
US-20250257046-A1 VITAMIN CATIONIC LIPIDS TRANSLATE BIO INC (US) 2025-08-14 — — US disclosed
US-20250255971-A1 ICE-BASED LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF MRNA TRANSLATE BIO, INC. 2025-08-14 — — US disclosed
EP-3621632-B1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2025-08-13 — — EP disclosed
US-20220257724-A1 DI-THIOESTER CATIONIC LIPIDS TRANSLATE BIO, INC. 2022-08-18 — — US disclosed
US-20220249699-A1 COMPOSITIONS AND METHODS FOR mRNA DELIVERY TRANSLATE BIO, INC. 2022-08-11 — — US disclosed
US-11407837-B2 GPCR binding proteins and synthesis thereof Twist Bioscience Corporation (US) 2022-08-09 — — US disclosed
US-20220233444-A1 THIOESTER CATIONIC LIPIDS TRANSLATE BIO, INC. 2022-07-28 — — US disclosed
US-20220226236-A1 Pulmonary Delivery of MRNA to Non-lung Target Cells RANA THERAPEUTICS, INC. 2022-07-21 — — US disclosed
US-20220226244-A1 MACROCYCLIC LIPIDS TRANSLATE BIO INC (US) 2022-07-21 — — US disclosed
US-20220177423-A1 CYSTINE CATIONIC LIPIDS TRANSLATE BIO, INC. 2022-06-09 — — US disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 — — US disclosed
US-20220073944-A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF TRANSLATE BIO, INC. 2022-03-10 — — US disclosed
US-20220071905-A1 PEG LIPIDOID COMPOUNDS TRANSLATE BIO, INC. 2022-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG NPY2R 3500/4885NPY4R 3663/4885NPY5R 4072/4885
US-20250257046-A1 VITAMIN CATIONIC LIPIDS APMAP, TTPA, CLN6 NPY2R 4443/4885NPY4R 4577/4885NPY5R 4620/4885
US-20220177423-A1 CYSTINE CATIONIC LIPIDS SLC7A11, SLC7A1, SLC7A5 NPY2R 3556/4885NPY4R 4102/4885NPY5R 3657/4885
US-20250255971-A1 ICE-BASED LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF MRNA CETP, SREBF2, NPC1L1 NPY2R 3668/4885NPY4R 3435/4885NPY5R 3045/4885
US-20220073944-A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF NSUN3, TRDMT1, NSUN2 NPY2R 2426/4885NPY4R 2483/4885NPY5R 1761/4885
US-20250288523-A1 PEG LIPIDOID COMPOUNDS LIPG, ABCB4, HDLBP NPY2R 4234/4885NPY4R 4133/4885NPY5R 4417/4885
US-12453759-B2 Di-thioester cationic lipids ACOT7, LYPLA2, LYPLA1 NPY2R 4214/4885NPY4R 3883/4885NPY5R 4516/4885
US-20220071905-A1 PEG LIPIDOID COMPOUNDS HDLBP, LIPG, ABCB4 NPY2R 4154/4885NPY4R 4018/4885NPY5R 4436/4885
US-20220233444-A1 THIOESTER CATIONIC LIPIDS CETP, ACOT7, LYPLA1 NPY2R 3640/4885NPY4R 3800/4885NPY5R 3946/4885
US-20220226244-A1 MACROCYCLIC LIPIDS SGMS1, NPC1L1, ABCB4 NPY2R 3702/4885NPY4R 4075/4885NPY5R 4333/4885
US-20220249699-A1 COMPOSITIONS AND METHODS FOR mRNA DELIVERY RNGTT, RNASE1, RNMT NPY2R 4152/4885NPY4R 4230/4885NPY5R 4127/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP NPY2R 1995/4885NPY4R 2452/4885NPY5R 2958/4885
US-20220257724-A1 DI-THIOESTER CATIONIC LIPIDS ACOT7, LYPLA2, LYPLA1 NPY2R 4214/4885NPY4R 3883/4885NPY5R 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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