Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL28519515 | 0.97 | TSHR (0.60) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Hexanoate SCHEMBL28080132 | 0.91 | AKR1B1 (0.70) | LMNATSHRAKR1B1GPR84PPARG | |
| Succinic Acid SCHEMBL2054178 | 0.89 | EGLN1 (0.53) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Myristic Acid SCHEMBL27706855 | 0.89 | GPR84 (0.71) | LMNATSHRAKR1B1GPR84PPARG | |
| Adipic Acid SCHEMBL28140166 | 0.83 | LMNA (0.73) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL28779741 | 0.83 | FFAR4 (0.44) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Butyric Acid SCHEMBL3206861 | 0.82 | FFAR3 (0.65) | TSHRAKR1B1GPR84PPARGPPARD | |
| SCHEMBL7180021 | 0.81 | LMNA (0.42) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL25265281 | 0.80 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL28562568 | 0.80 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114058210-B | Water-based photo-curing ink composition, and preparation method and application thereof | 安徽省高泰新材料有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-114539856-A | Non-stick coating and preparation method and application thereof | 无锡康庭氟塑材料科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114231145-A | Moisture-resistant waterproof primer for plastic track and preparation method of moisture-resistant waterproof primer | 广州市盛邦康体场地材料有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-114058210-A | Water-based photo-curing ink composition, and preparation method and application thereof | 安徽省高泰新材料有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113512328-A | Exterior wall coating composition, exterior wall coating and preparation method thereof | 北京石墨烯研究院有限公司 | 2021-10-19 | — | — | CN | claimed |
| CN-110947903-B | Modified composition of adhesive for titanium alloy investment casting and application thereof | 湖南洛兰新材料有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-110947903-A | Modified composition of adhesive for titanium alloy investment casting and application thereof | 湖南洛兰新材料有限公司 | 2020-04-03 | — | — | CN | claimed |
| CN-112239610-B | Carbon additive for organic coating, and heat-generating component | 青岛海尔智能技术研发有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-114539856-A | Non-stick coating and preparation method and application thereof | 无锡康庭氟塑材料科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114231145-A | Moisture-resistant waterproof primer for plastic track and preparation method of moisture-resistant waterproof primer | 广州市盛邦康体场地材料有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-113604173-B | Water-soluble adhesive, preparation method thereof and woven mesh tube | 深圳市骏鼎达新材料股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-114058210-A | Water-based photo-curing ink composition, and preparation method and application thereof | 安徽省高泰新材料有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113604173-A | Water-soluble adhesive, preparation method thereof and woven mesh tube | 深圳市骏鼎达新材料股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-112239610-A | Carbon additive for organic coating, and heat-generating component | 青岛海尔智能技术研发有限公司 | 2021-01-19 | — | — | CN | disclosed |
| CN-110947903-A | Modified composition of adhesive for titanium alloy investment casting and application thereof | 湖南洛兰新材料有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-110947903-A | Modified composition of adhesive for titanium alloy investment casting and application thereof | 湖南洛兰新材料有限公司 | 2020-04-03 | — | — | CN | disclosed |
| CN-110643256-A | Water-based environment-friendly wall paint capable of being repeatedly written with water and preparation method thereof | 山西大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-2392314-B1 | OILY HAIR COSMETIC | KOKYU ALCOHOL KOGYO CO LTD (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-7766978-B2 | Acidic hair dyeing method | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | KOKYU ALCOHOL KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100609-A1 | ACIDIC HAIR DYE COMPOSITION | H1-0, MRM1, H1-4 | LMNA 1060/4885TSHR 3886/4885NFKB1 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.