⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30834436 | 0.98 | ALDH1A1 (0.50) | — | |
| SCHEMBL10968213 | 0.92 | ALDH1A1 (0.50) | — | |
| Diethylamine SCHEMBL10666196 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL89139 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL31194817 | 0.80 | ALDH1A1 (0.50) | — | |
| Pyridine SCHEMBL8587106 | 0.74 | ALDH1A1 (0.48) | — | |
| Benzo[D]Thiazole SCHEMBL27256307 | 0.71 | ALDH1A1 (0.83) | — | |
| Benzo[D]Thiazole SCHEMBL451685 | 0.69 | — | — | |
| SCHEMBL209182 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546155-A | Pleuromutilin derivative containing thiazolo [5,4-C ] pyridine side chain and preparation method and application thereof | 西安康诺化工有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-113679717-B | Methods for inhibiting fascin | 康奈尔大学 | 2026-05-22 | — | — | CN | disclosed |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | disclosed |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | disclosed |
| CN-115843295-B | NAMPT modulators | 赛特凯恩蒂克公司 | 2025-04-15 | — | — | CN | disclosed |
| EP-4508052-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2025-02-19 | — | — | EP | disclosed |
| CN-119451951-A | Compounds for inhibition of KIF18A | 沃拉斯查疗法公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119241504-A | Spiroindoline inhibitors of KIF18A | 沃拉斯查疗法公司 | 2025-01-03 | — | — | CN | disclosed |
| US-12162895-B2 | DNA polymerase theta inhibitor for treatment of cancer | BREAKPOINT THERAPEUTICS GMBH (DE) | 2024-12-10 | — | — | US | disclosed |
| CN-118955409-A | Cardiac sarcomere inhibitors | 赛特凯恩蒂克公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-111349087-B | Compounds and methods for inhibiting fascin | 康奈尔大学 | 2023-07-14 | — | — | CN | disclosed |
| US-11673888-B2 | Bicyclic compounds as ATX inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2023-06-13 | — | — | US | disclosed |
| CN-107108534-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115996912-A | Iminothiolanone inhibitors of ENPP1 | 沃拉斯查疗法公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115843295-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115515934-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115477659-A | Edoxaban intermediate compound | 山东新时代药业有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113105446-B | Preparation method of carbon-nucleoside compound | 南京方生和医药科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| WO-2022158610-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-07-28 | — | — | WO | disclosed |
| WO-2022075486-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-04-14 | — | — | WO | disclosed |