Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011770 | 1.00 | THRA (0.48) | THRATHRBCXCR4GAAMEN1 | |
| SCHEMBL109040 | 0.88 | GAA (0.50) | GAAMEN1ABL1ALPLKMT2A | |
| Levodopa SCHEMBL11500329 | 0.85 | SLC7A5 (0.63) | THRATHRBCXCR4MEN1KMT2A | |
| SCHEMBL11686246 | 0.83 | THRA (0.50) | THRATHRBCXCR4GAAMEN1 | |
| SCHEMBL15978114 | 0.83 | CYP19A1 (0.45) | GAAMEN1ABL1ALPLKMT2A | |
| SCHEMBL30020046 | 0.83 | CYP19A1 (0.45) | GAAMEN1ABL1ALPLKMT2A | |
| SCHEMBL9819566 | 0.83 | SHBG (0.50) | THRATHRBGAAMEN1KMT2A | |
| SCHEMBL25471931 | 0.82 | IGF1R (0.47) | CXCR4GAAMEN1ABL1ALPL | |
| SCHEMBL1012031 | 0.81 | CXCR4 (0.53) | THRATHRBCXCR4GAADRD2 | |
| SCHEMBL28722955 | 0.81 | CXCR4 (0.53) | THRATHRBCXCR4GAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | disclosed |