Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857118 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL29601544 | 0.87 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL30620798 | 0.87 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL28054466 | 0.87 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL28269615 | 0.87 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL30789010 | 0.85 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL28857086 | 0.85 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL29601011 | 0.85 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| SCHEMBL29140304 | 0.85 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 | |
| Fumaric Acid SCHEMBL21931373 | 0.84 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149412-A | Intermediate compound for preparing Vonoprazan | 鲁南制药集团股份有限公司 | 2022-03-08 | — | — | CN | disclosed |