Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13762090 | 1.00 | MEN1 (0.70) | MEN1KMT2AHPGDLMNARAB9A | |
| SCHEMBL3817884 | 0.85 | CA2 (0.70) | MEN1KMT2AHPGDRAB9ACA2 | |
| SCHEMBL6570852 | 0.84 | CA2 (0.69) | MEN1KMT2ACA2HDAC3HDAC8 | |
| SCHEMBL6858815 | 0.81 | LMNA (0.56) | MEN1KMT2AHPGDLMNARAB9A | |
| SCHEMBL4159641 | 0.80 | KMT2A (0.69) | MEN1KMT2AHPGDLMNARAB9A | |
| SCHEMBL7113776 | 0.79 | RAB9A (1.00) | MEN1KMT2ALMNARAB9AEPHX2 | |
| SCHEMBL1709278 | 0.78 | MEN1 (0.57) | MEN1KMT2AHPGDCA2MAPT | |
| SCHEMBL28042188 | 0.78 | HDAC2 (0.69) | MEN1KMT2AHPGDLMNARAB9A | |
| SCHEMBL9312706 | 0.77 | LMNA (0.60) | MEN1KMT2ALMNARAB9AEPHX2 | |
| SCHEMBL13988501 | 0.76 | CA2 (0.56) | MEN1KMT2AHPGDCA2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369039-A | Preparation method of butenafine intermediate | 鲁南制药集团股份有限公司 | 2022-04-19 | — | — | CN | disclosed |