Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265277 | 0.77 | LMNA (0.39) | CHRM1CHRM2CHRM5CHRM3CHRM4 | |
| SCHEMBL10355569 | 0.75 | LMNA (0.36) | LMNA | |
| SCHEMBL503732 | 0.73 | LMNA (0.35) | CHRM1CHRM2CHRM3LMNA | |
| SCHEMBL7871647 | 0.72 | CHRM1 (0.65) | CHRM1CHRM2CHRM5CHRM3CHRM4 | |
| SCHEMBL8781384 | 0.70 | LMNA (0.35) | CHRM1CHRM2CHRM3LMNA | |
| SCHEMBL5493343 | 0.69 | LMNA (0.34) | LMNAPOLB | |
| SCHEMBL10715542 | 0.68 | CHRM3 (0.39) | CHRM1CHRM2CHRM5CHRM3CHRM4 | |
| SCHEMBL29403400 | 0.68 | CHRM1 (0.63) | CHRM1CHRM2CHRM5CHRM3CHRM4 | |
| SCHEMBL7281820 | 0.68 | CYP2D6 (0.40) | KMT2ALMNAMEN1POLBTSHR | |
| SCHEMBL7349981 | 0.67 | LMNA (0.32) | CHRM1CHRM2CHRM3KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3996644-A1 | MULTI-AGENT OCULAR FORMULATIONS AND TREATMENT METHODS | University of Utah Research Foundation (US) | 2022-05-18 | — | — | EP | disclosed |