Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601461 | 0.87 | SQOR (0.34) | SQORL3MBTL1OXER1NPC1GLA | |
| SCHEMBL29601208 | 0.82 | HDAC1 (0.43) | SQORHDAC1HDAC2L3MBTL1NPC1 | |
| SCHEMBL29601253 | 0.81 | HDAC1 (0.44) | SQORHDAC1HDAC2OXER1ELANE | |
| SCHEMBL28654970 | 0.78 | HDAC1 (0.36) | HDAC1HDAC2MAPK1P2RX7KMT2A | |
| SCHEMBL29601213 | 0.73 | HDAC1 (0.42) | SQORHDAC1HDAC2L3MBTL1NPC1 | |
| SCHEMBL24476506 | 0.72 | ADORA2A (0.38) | HDAC1HDAC2MEN1KMT2ATDP1 | |
| SCHEMBL28649295 | 0.72 | ADORA2A (0.38) | HDAC1HDAC2MEN1KMT2ATDP1 | |
| SCHEMBL29601164 | 0.72 | HDAC1 (0.35) | SQORHDAC1HDAC2L3MBTL1NPC1 | |
| SCHEMBL28669450 | 0.72 | ADORA2A (0.40) | HDAC1HDAC2NPC1POLBMEN1 | |
| SCHEMBL24476655 | 0.69 | TNF (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |