Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601253 | 0.99 | HDAC1 (0.44) | HDAC1HDAC2P2RX7LMNATP53 | |
| SCHEMBL29601213 | 0.88 | HDAC1 (0.42) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL29601164 | 0.87 | HDAC1 (0.35) | HDAC1HDAC2P2RX7TP53ALDH1A1 | |
| SCHEMBL29601330 | 0.82 | SQOR (0.35) | HDAC1HDAC2P2RX7TDP1SQOR | |
| SCHEMBL28669352 | 0.77 | P2RX7 (0.37) | HDAC1HDAC2P2RX7LMNATP53 | |
| SCHEMBL5347874 | 0.73 | PNP (0.50) | SQOR | |
| SCHEMBL5161068 | 0.72 | HDAC1 (0.51) | HDAC1HDAC2P2RX7ALDH1A1TDP1 | |
| SCHEMBL29601461 | 0.72 | SQOR (0.34) | LMNAALDH1A1MAPTTDP1SQOR | |
| SCHEMBL9537822 | 0.72 | KMT2A (0.44) | SQORGSK3B | |
| SCHEMBL24476294 | 0.72 | P2RX7 (0.41) | HDAC1HDAC2P2RX7LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |