Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.34 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601330 | 0.87 | SQOR (0.35) | SQOROXER1L3MBTL1NPC1GLA | |
| SCHEMBL29601164 | 0.82 | HDAC1 (0.35) | SQORL3MBTL1NPC1GLAMAPK1 | |
| SCHEMBL29601208 | 0.72 | HDAC1 (0.43) | SQORL3MBTL1NPC1GLAMAPK1 | |
| SCHEMBL29601253 | 0.71 | HDAC1 (0.44) | SQOROXER1ELANETDP1ALDH1A1 | |
| SCHEMBL24476301 | 0.69 | KAT2B (0.43) | MAPK1FAAH | |
| SCHEMBL29601165 | 0.68 | TLR8 (0.40) | L3MBTL1POLB | |
| SCHEMBL29601423 | 0.67 | ALDH1A1 (0.36) | NPC1MAPK1POLBRAB9AALDH1A1 | |
| SCHEMBL28654970 | 0.66 | HDAC1 (0.36) | MAPK1KMT2AFAAHLMNAMAPT | |
| SCHEMBL29601213 | 0.66 | HDAC1 (0.42) | SQORL3MBTL1NPC1GLAMAPK1 | |
| SCHEMBL684387 | 0.64 | MAPK1 (0.60) | MAPK1POLBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |