Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205451 | 0.79 | ALDH1A1 (0.43) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL1703171 | 0.74 | ALOX15 (0.38) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL28994161 | 0.74 | OPRM1 (0.56) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL27035066 | 0.74 | HDAC4 (0.49) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL30678364 | 0.74 | OPRM1 (0.56) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL29710660 | 0.74 | ALOX15 (0.38) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4069650 | 0.74 | OPRL1 (0.40) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL17982827 | 0.74 | OPRM1 (0.56) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL30678365 | 0.74 | OPRM1 (0.56) | SIGMAR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL17733195 | 0.73 | MEN1 (0.41) | SIGMAR1ADORA3TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237404-A1 | NOVEL COMPOUNDS | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090724-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |