Benzosampangine

Benzosampangine

SCHEMBL29601408

O=C1c2ccccc2-c2nccc3c2c1nc1ccccc13

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 6/20 0.79
MAOA P21397 2/20 0.56
TERT O14746 1/20 0.55
ALDH1A1 P00352 2/20 0.54
RAB9A P51151 4/20 0.53
NPC1 O15118 3/20 0.53
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
AHR P35869 1/20 0.53
IDO1 P14902 1/20 0.46
CTSL P07711 1/20 0.45
PTPRC P08575 1/20 0.45
CTSS P25774 1/20 0.45
PTPN13 Q12923 1/20 0.45
MAPK1 P28482 1/20 0.42
ESR1 P03372 1/20 0.41
TP53 P04637 1/20 0.41
PTK2B Q14289 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzosampangine SCHEMBL20259217 1.00 TOP2A (0.79) TOP2AMAOATERTALDH1A1RAB9A
SCHEMBL7635167 0.88 TOP2A (0.80) TOP2AMAOATERTALDH1A1RAB9A
Ascididemin SCHEMBL30547678 0.88 TOP2A (1.00) TOP2AMAOATERTALDH1A1RAB9A
Ascididemin SCHEMBL6841381 0.88 TOP2A (1.00) TOP2AMAOATERTALDH1A1RAB9A
SCHEMBL20259026 0.88 TOP2A (0.66) TOP2AMAOATERTALDH1A1RAB9A
SCHEMBL20259025 0.85 TOP2A (0.59) TOP2AMAOATERTALDH1A1RAB9A
SCHEMBL7186247 0.82 TOP2A (0.75) TOP2AMAOATERTALDH1A1RAB9A
SCHEMBL20258991 0.81 TOP2A (0.72) TOP2AMAOATERTALDH1A1RAB9A
SCHEMBL22144889 0.79 TOP2A (0.66) TOP2AMAOATERTRAB9ANPC1
SCHEMBL16072070 0.77 TOP2A (0.64) TOP2AMAOATERTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12546775-B2 Peptides, reagents and methods for detecting food allergy AllerGenis, Inc. (US) 2026-02-10 US disclosed
EP-4001920-A1 PEPTIDES AND METHODS FOR DETECTING FOOD ALLERGY AllerGenis, LLC (US) 2022-05-25 EP disclosed
US-20220155296-A1 Peptides, Reagents And Methods For Detecting Food Allergy AllerGenis, Inc. 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12546775-B2 Peptides, reagents and methods for detecting food allergy HLA-DRB1, IL33, SERPINA6 TOP2A 3821/4885MAOA 4782/4885TERT 4566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.