Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601441 | 0.89 | GAA (0.72) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL14236785 | 0.87 | ALDH1A1 (0.78) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL15172174 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL14236801 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL14324542 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL2946066 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL2944851 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4EL3MBTL1BLMSMN1; SMN2 | |
| SCHEMBL11299599 | 0.83 | PKM (0.52) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL29753302 | 0.82 | PKM (0.51) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL12311741 | 0.81 | HPGD (0.65) | ALDH1A1SMN1; SMN2TSHRHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VHL, TP53, ASAH2 | ALDH1A1 238/4885KDM4E 3146/4885L3MBTL1 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.