SCHEMBL29601465

SCHEMBL29601465

Cc1c(S(=O)(=O)c2cc(N)c(N)c(C)c2C)cc(N)c(N)c1C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.38
CDC25B P30305 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
APEX1 P27695 1/20 0.32
CYP2C19 P33261 1/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27866682 1.00 KDM4E (0.40) KDM4EALDH1A1GAACDC25BL3MBTL1
SCHEMBL3290542 0.73 GAA (0.42) KDM4EALDH1A1GAACDC25BL3MBTL1
SCHEMBL9318932 0.73 KDM4E (0.45) KDM4EALDH1A1GAACDC25BL3MBTL1
SCHEMBL6313324 0.70 GAA (0.44) KDM4EALDH1A1GAACDC25BL3MBTL1
SCHEMBL10588480 0.70 L3MBTL1 (0.42) KDM4EALDH1A1GAAL3MBTL1CYP2C19
SCHEMBL29162279 0.69 RAPGEF4 (0.40) KDM4EALDH1A1L3MBTL1CYP2C19PKM
SCHEMBL2097314 0.68 PTK2 (0.47) KDM4EALDH1A1GAA
SCHEMBL10407535 0.68 KDM4E (0.36) KDM4EALDH1A1GAA
SCHEMBL12339906 0.68 ALDH1A1 (0.42) KDM4EALDH1A1GAACDC25BL3MBTL1
SCHEMBL476444 0.67 CYP3A4 (0.48) KDM4EALDH1A1GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022082425-A1 INKJET-USE HARDENABLE COMPOSITION, HARDENER, AND FLEXIBLE PRINTED CIRCUIT BOARD 律胜科技股份有限公司 2022-04-28 WO disclosed