Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.69 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | VEGFA | P15692 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27039728 | 1.00 | FTO (0.69) | FTOEGLN2EGLN1GAAVEGFA | |
| SCHEMBL10709742 | 0.84 | EGLN2 (0.49) | FTOEGLN2CTSA | |
| SCHEMBL13310736 | 0.83 | PARP1 (0.48) | FTOEGLN2 | |
| SCHEMBL704958 | 0.82 | FTO (1.00) | FTOEGLN2EGLN1VEGFAFLT1 | |
| SCHEMBL29601361 | 0.82 | ALDH1A1 (0.51) | FTOEGLN2 | |
| SCHEMBL3958929 | 0.81 | KMT2A (0.61) | EGLN1GAA | |
| SCHEMBL8883374 | 0.81 | FTO (0.69) | FTOEGLN2EGLN1GAAKDM5B | |
| SCHEMBL22804019 | 0.81 | FTO (0.69) | FTOEGLN2EGLN1GAAKDM5B | |
| SCHEMBL704947 | 0.80 | EGLN2 (0.64) | FTOEGLN2EGLN1GAACTSA | |
| SCHEMBL109198 | 0.80 | P2RX7 (0.59) | FTOEGLN2GAACTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |