Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228051 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| Methyl Anthranilate SCHEMBL28199302 | 0.92 | ALDH1A1 (0.74) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| SCHEMBL2895994 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| Naphthoquinone SCHEMBL28199224 | 0.86 | PTPRC (0.54) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| SCHEMBL20711002 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| SCHEMBL27613393 | 0.85 | CYP2D6 (0.48) | ALDH1A1HSD17B10CFTRTSHRCYP2D6 | |
| Methyl Anthranilate SCHEMBL5013272 | 0.84 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| Methyl Anthranilate SCHEMBL29614281 | 0.84 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| O-Xylene SCHEMBL28521237 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRLMNATSHR | |
| SCHEMBL27902531 | 0.83 | CYP2C9 (0.47) | ALDH1A1HSD17B10CFTRTSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526292-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | Biogen MA Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-117800916-B | Preparation and application of 1- [ (1H-indazol-7-yl) methyl ] -3-arylthiourea derivative | 沈阳药科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. | 2024-02-22 | — | — | US | disclosed |
| WO-2023225244-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| CN-114585715-A | Home care products or formulations | 西姆莱斯有限公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-3986871-A1 | QUINAZOLINE PRODRUGS FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | KRAS, HRAS, APC | ALDH1A1 1221/4885HSD17B10 2525/4885CFTR 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.