SCHEMBL29602178

SCHEMBL29602178

OCCNCc1ccc(OCc2ccccc2)c(OCCc2ccccc2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 1/20 0.71
▸ BCHE P06276 4/20 0.62
▸ SMN1; SMN2 Q16637 4/20 0.58
▸ LMNA P02545 4/20 0.58
▸ HTT P42858 3/20 0.58
▸ KDM4E B2RXH2 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ USP28 Q96RU2 1/20 0.56
▸ USP25 Q9UHP3 1/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ NPY1R P25929 1/20 0.56
▸ NPY2R P49146 1/20 0.56
▸ MEN1 O00255 2/20 0.53
▸ GAA P10253 1/20 0.53
▸ ATM Q13315 1/20 0.51
▸ C5AR1 P21730 1/20 0.51
▸ HTR1A P08908 1/20 0.50
▸ HTR7 P34969 1/20 0.50
▸ HTR6 P50406 1/20 0.50
▸ NLRP3 Q96P20 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21427198 1.00 SLC2A1 (0.71) SLC2A1BCHESMN1; SMN2LMNAHTT
Hydrochloric Acid SCHEMBL29051153 0.99 SLC2A1 (0.70) SLC2A1BCHESMN1; SMN2LMNAHTT
Hydrochloric Acid SCHEMBL30467188 0.99 SLC2A1 (0.70) SLC2A1BCHESMN1; SMN2LMNAHTT
SCHEMBL21426904 0.95 SLC2A1 (0.62) SLC2A1BCHESMN1; SMN2LMNAHTT
SCHEMBL21410029 0.94 SLC2A1 (0.70) SLC2A1BCHESMN1; SMN2LMNAHTT
SCHEMBL30467194 0.94 SLC2A1 (0.70) SLC2A1BCHESMN1; SMN2LMNAHTT
Hydrochloric Acid SCHEMBL21410031 0.94 SLC2A1 (0.61) SLC2A1BCHESMN1; SMN2LMNAHTT
Hydrochloric Acid SCHEMBL21410028 0.93 SLC2A1 (0.68) SLC2A1BCHESMN1; SMN2LMNAHTT
SCHEMBL21410033 0.93 SLC2A1 (0.68) SLC2A1BCHESMN1; SMN2LMNAHTT
SCHEMBL30467196 0.93 SLC2A1 (0.68) SLC2A1BCHESMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112105598-B Compounds for preventing or treating obesity or metabolic syndrome and pharmaceutical compositions comprising the same 普罗泰克株式会社 2023-06-27 — — CN claimed
CN-112424160-B Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same 奧土择破利悟株式会社 2024-03-08 — — CN disclosed
CN-112105598-B Compounds for preventing or treating obesity or metabolic syndrome and pharmaceutical compositions comprising the same 普罗泰克株式会社 2023-06-27 — — CN disclosed
US-20220323379-A1 P62 LIGAND COMPOUND AND ER-PHAGY-PROMOTING USE THEREOF Protech, Inc. (KR) 2022-10-13 — — US disclosed
CN-114641282-A P62 ligand compound and ER-autophagy promoting use thereof 普罗泰克株式会社 2022-06-17 — — CN disclosed
EP-3988090-A1 P62 LIGAND COMPOUND AND ER-PHAGY-PROMOTING USE THEREOF Protech Inc. (KR) 2022-04-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220323379-A1 P62 LIGAND COMPOUND AND ER-PHAGY-PROMOTING USE THEREOF SQSTM1, ATG7, TFEB SLC2A1 2992/4885BCHE 4621/4885SMN1; SMN2 2848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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