Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737560 | 1.00 | MAPT (0.52) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL8626133 | 1.00 | MAPT (0.52) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL28022421 | 1.00 | MAPT (0.52) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL11735326 | 0.97 | — | — | |
| SCHEMBL270929 | 0.90 | — | — | |
| SCHEMBL12114194 | 0.82 | TRPA1 (0.65) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL28354972 | 0.82 | TRPA1 (0.65) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL25237189 | 0.81 | TRPA1 (0.59) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL215822 | 0.81 | TRPA1 (0.59) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL21552047 | 0.81 | TRPA1 (0.59) | MAPTTRPA1DDAH1GAPDHFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143988-A1 | NEW COMPOUNDS AND THEIR USE AS ANTI-AGING AGENT OR AS EXERCISE ENHANCER | ETH ZURICH (CH) | 2023-08-03 | — | — | WO | disclosed |
| EP-2921157-B1 | Coated titanium dioxide to reduce whitening effect on skin | SYMRISE AG (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2185126-B1 | USE OF TROXERUTIN TO QUENCH THE FLUORESCENCE OF DISODIUM PHENYL DIBENZIMIDAZOLE TETRASULFONATE | SYMRISE AG (DE) | 2017-06-21 | — | — | EP | disclosed |
| US-9517190-B2 | Coated titanium dioxide to reduce the whitening effect on skin | SYMRISE AG (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2178493-B2 | Stable soluble salts of phenylbenzimidazole sulfonic acid at pH 6.0 to below 6.8 | SYMRISE AG (DE) | 2015-12-09 | — | — | EP | disclosed |
| EP-2939710-A1 | Method to reduce substantivity of cloth staining caused by sunscreens | Symrise AG (DE) | 2015-11-04 | — | — | EP | disclosed |
| WO-2015139782-A1 | COATED TITANIUM DIOXIDE TO REDUCE THE WHITENING EFFECT ON SKIN | SYMRISE AG (DE) | 2015-09-24 | — | — | WO | disclosed |
| US-20150265510-A1 | COATED TITANIUM DIOXIDE TO REDUCE THE WHITENING EFFECT ON SKIN | SYMRISE AG (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-2921157-A1 | Coated titanium dioxide to reduce whitening effect on skin | Symrise AG (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-8440172-B2 | Stable soluble salts of phenylbenzimidazole sulfonic acid at PHS at or below 7.0 | SYMRISE AG (DE) | 2013-05-14 | — | — | US | disclosed |
| US-3988361-A | HYPOTENSIVE AGENTS, ANTILIPOLYTIC AGENTS; PROSTAGLANDIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3987083-A | ANTIULCER, ANTICOAGULANTS, ABORTION, DECONGESTANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3983153-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3983155-A | Racemic prostaglandins of the 2-series and analogs thereof | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3983154-A | Racemic prostaglandins of the 2-series and analogs thereof | THE UPJOHN COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3981880-A | ANTIULCER, ANTICOAGULANT, WOUND HEALING, ABORTION | THE UPJOHN COMPANY (US) | 1976-09-21 | — | — | US | disclosed |
| US-3980691-A | ANTIULCER, INHIBITION OF PLATELET AGGRESSION, INCREASE OF NASAL PATENCY, ABORTION, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
| US-3974200-A | ANTIULCER, INHIBIT PLATELET AGGREGATION, NASAL PATENCY, ABORTION, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
| US-3959346-A | Racemic prostaglandins of the 2-series and analogs thereof | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
| US-3936487-A | RACEMIC MIXTURES, ANTIULCER, ANTICOAGULANT, LABOR INDUCING | THE UPJOHN COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265510-A1 | COATED TITANIUM DIOXIDE TO REDUCE THE WHITENING EFFECT ON SKIN | FASN, ALOX12, CUTA | MAPT 1508/4885TRPA1 1014/4885DDAH1 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.