Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.30 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.30 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29604663 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL29603429 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL24440341 | 0.83 | ALDH1A1 (0.31) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29603956 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29603887 | 0.79 | L3MBTL1 (0.39) | ALDH1A1MAPTPTGS2TNFPTGS1 | |
| SCHEMBL24439279 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL29603838 | 0.74 | GSR (0.38) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL24440547 | 0.71 | MAPT (0.35) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL29604031 | 0.70 | PTGS2 (0.36) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL24440325 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TDP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103281-A1 | METHANOGEN INHIBITORS | PASTORAL GREENHOUSE GAS RESEARCH LTD (NZ) | 2022-05-19 | — | — | WO | disclosed |