Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012744 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL14415281 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7838214 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL28529030 | 0.74 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27840661 | 0.70 | SLC6A2 (0.35) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6050232 | 0.69 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5100742 | 0.69 | SLC6A3 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL14964824 | 0.68 | SLC6A2 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL17243210 | 0.68 | SLC6A3 (0.45) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL16084898 | 0.66 | SLC6A2 (0.40) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754694-B2 | Pyrrolo[2, 1-C][1, 4]benzodiazepine-glycoside prodrug useful as a selective anti tumor agent | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-13 | — | — | US | claimed |
| EP-2188297-A1 | PYRROLO Ý2,1-C¨Ý1, 4¨BENZODIAZEPINE-GLYCOSIDE PRODRUGS USEFUL AS A SELECTIVE ANTI TUMOR AGENT | Council of Scientific & Industrial Research (IN) | 2010-05-26 | — | — | EP | claimed |
| WO-2009016647-A1 | PYRROLO [2,1-C][1, 4] BENZODIAZEPINE-GLYCOSIDE PRODRUGS USEFUL AS A SELECTIVE ANTI TUMOR AGENT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-02-05 | — | — | WO | claimed |
| US-7754694-B2 | Pyrrolo[2, 1-C][1, 4]benzodiazepine-glycoside prodrug useful as a selective anti tumor agent | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-13 | — | — | US | disclosed |
| EP-2188297-A1 | PYRROLO Ý2,1-C¨Ý1, 4¨BENZODIAZEPINE-GLYCOSIDE PRODRUGS USEFUL AS A SELECTIVE ANTI TUMOR AGENT | Council of Scientific & Industrial Research (IN) | 2010-05-26 | — | — | EP | disclosed |
| US-20090036657-A1 | PYRROLO[2, 1-C][1, 4]BENZODIAZEPINE-GLYCOSIDE PRODRUG USEFUL AS A SELECTIVE ANTI TUMOR AGENT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-02-05 | — | — | US | disclosed |
| WO-2009016647-A1 | PYRROLO [2,1-C][1, 4] BENZODIAZEPINE-GLYCOSIDE PRODRUGS USEFUL AS A SELECTIVE ANTI TUMOR AGENT | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008099416-A2 | NOVEL BENZOTHIAZOLE AND BENZOXAZOLE LINKED PYRROLO[2,1-C] [1, 4] BENZODIAZEPINE HYBRIDS AS NOVEL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036657-A1 | PYRROLO[2, 1-C][1, 4]BENZODIAZEPINE-GLYCOSIDE PRODRUG USEFUL AS A SELECTIVE ANTI TUMOR AGENT | GLB1, PYGL, PLG | SLC6A2 3878/4885SLC6A3 3501/4885SLC6A4 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.