Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | BMP1 | P13497 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737969 | 0.99 | GLO1 (0.41) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL29670039 | 0.92 | FOLH1 (0.46) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL30658618 | 0.92 | FOLH1 (0.49) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL29590533 | 0.90 | NOD1 (0.41) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL11133652 | 0.90 | PTGS1 (0.45) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL30099590 | 0.89 | GLO1 (0.46) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL29431016 | 0.88 | PTGS1 (0.44) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL29888861 | 0.88 | PTGS1 (0.43) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL31479950 | 0.88 | GLO1 (0.43) | FOLH1RIMKLANAALAD2PTGS1GSTK1 | |
| SCHEMBL29814935 | 0.87 | GLO1 (0.43) | FOLH1RIMKLANAALAD2PTGS1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174903-B1 | BISPECIFIC SINGLE CHAIN ANTIBODY CONSTRUCT WITH ENHANCED TISSUE DISTRIBUTION | AMGEN RES MUNICH GMBH (DE) | 2024-04-10 | — | — | EP | claimed |
| US-20260116972-A1 | CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODY | AMGEN RES MUNICH GMBH (DE) | 2026-04-30 | — | — | US | disclosed |
| US-20230357444-A1 | CROSS-SPECIES-SPECIFIC BINDING DOMAIN | AMGEN RES MUNICH GMBH (DE) | 2023-11-09 | — | — | US | disclosed |
| EP-4243936-A1 | METHODS FOR ADMINISTERING A BCMA X CD3 BINDING MOLECULE | Amgen Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| CN-116063541-A | Bispecific antibody constructs for CDH3 and CD3 | 安进研发（慕尼黑）股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-4161969-A1 | BISPECIFIC BINDING CONSTRUCTS | Amgen Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022103781-A1 | METHODS FOR ADMINISTERING A BCMA X CD3 BINDING MOLECULE | AMGEN INC. (US) | 2022-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116972-A1 | CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODY | MET, IGF1R, INHA | FOLH1 45/4885RIMKLA 4143/4885NAALAD2 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.