Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22832649 | 0.88 | CTSD (0.35) | HSD11B1BACE1CTSD | |
| SCHEMBL30520964 | 0.87 | HSD11B1 (0.38) | HSD11B1BACE1CTSD | |
| SCHEMBL29606090 | 0.85 | BACE1 (0.32) | BACE1CTSD | |
| SCHEMBL30374023 | 0.85 | HSD11B1 (0.32) | HSD11B1BACE1CTSD | |
| SCHEMBL30728152 | 0.85 | HSD11B1 (0.44) | HSD11B1BACE1CTSD | |
| SCHEMBL25178762 | 0.85 | HSD11B1 (0.32) | HSD11B1BACE1CTSD | |
| SCHEMBL29614312 | 0.85 | HSD11B1 (0.41) | HSD11B1BACE1CTSD | |
| SCHEMBL25411577 | 0.85 | HSD11B1 (0.44) | HSD11B1BACE1CTSD | |
| SCHEMBL31274980 | 0.84 | CHRNA1 (0.32) | BACE1CTSD | |
| SCHEMBL25311812 | 0.84 | HSD11B1 (0.35) | HSD11B1BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364670-B | Substituted benzyl-triazole compound for Cbl-b inhibition and further application thereof | 纽力克斯治疗公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2024255762-A1 | CBL-B INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2024-12-19 | — | — | WO | disclosed |
| EP-3990117-A1 | SUBSTITUTED BENZYL-TRIAZOLE COMPOUNDS FOR CBL-B INHIBITION, AND FURTHER USES THEREOF | Nurix Therapeutics, Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-114364670-A | Substituted benzyl-triazoles for Cbl-b inhibition and further uses thereof | 纽力克斯治疗公司 | 2022-04-15 | — | — | CN | disclosed |