Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614312 | 0.95 | HSD11B1 (0.41) | HSD11B1HSD11B2CTSDBACE1NR1I2 | |
| SCHEMBL30728152 | 0.95 | HSD11B1 (0.44) | HSD11B1HSD11B2CTSDBACE1NR1I2 | |
| SCHEMBL25411577 | 0.95 | HSD11B1 (0.44) | HSD11B1HSD11B2CTSDBACE1NR1I2 | |
| SCHEMBL22832649 | 0.90 | CTSD (0.35) | HSD11B1HSD11B2CTSDBACE1 | |
| SCHEMBL30374023 | 0.89 | HSD11B1 (0.32) | HSD11B1CTSDBACE1 | |
| SCHEMBL25178762 | 0.89 | HSD11B1 (0.32) | HSD11B1CTSDBACE1 | |
| SCHEMBL22832590 | 0.88 | CHRNA1 (0.34) | HSD11B1CTSDBACE1 | |
| SCHEMBL25179647 | 0.87 | HSD11B1 (0.31) | HSD11B1CTSDBACE1 | |
| SCHEMBL29605058 | 0.87 | HSD11B1 (0.34) | HSD11B1CTSDBACE1 | |
| SCHEMBL30374120 | 0.87 | HSD11B1 (0.31) | HSD11B1CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151640-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |