SCHEMBL296058

SCHEMBL296058

C[Si](Oc1ccccc1)(Oc1ccccc1)C1CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200187 0.83 KDM4E (0.35) KDM4ETSHRKMT2A
SCHEMBL18587310 0.78 KDM4E (0.32) KDM4ETSHR
SCHEMBL6701075 0.76 KDM4E (0.36) KDM4ETSHRMEN1KMT2A
SCHEMBL20365074 0.75 ALDH1A1 (0.32) KDM4ETSHRKMT2A
SCHEMBL6750638 0.75 KDM4E (0.36) KDM4ETSHRMEN1KMT2A
SCHEMBL2605522 0.73 KDM4E (0.30) KDM4E
SCHEMBL949048 0.73 ALDH1A1 (0.32) KDM4E
SCHEMBL18560853 0.72 KDM4E (0.32) KDM4ETSHR
SCHEMBL21525762 0.72 KDM4E (0.32) KDM4ETSHRMEN1KMT2A
SCHEMBL21525765 0.72 KDM4E (0.32) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1223195-B1 Thermoplastic resin composition and shaped articles thereof JSR CORP (JP) 2012-03-14 EP disclosed
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070112158-A1 Novel (co)polymer, process for producing the same, and process for producing carboxylated (co)polymer JSR CORPORATION (JP) 2007-05-17 US disclosed
EP-1686139-A1 NOVEL (CO)POLYMER, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING CARBOXYLATED (CO)POLYMER JSR Corporation (JP) 2006-08-02 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed
US-6562908-B2 Blend of rubber reinforced thermoplastic resins, acrylic resins and thermoplastic norbornene resins; heat resistance, strength, processability, and laser marking properties JSR CORPORATION (JP) 2003-05-13 US disclosed
US-20020128392-A1 Thermoplastic resin composition and shaped articles thereof JSR CORPORATION (JP) 2002-09-12 US disclosed
EP-1223195-A2 Thermoplastic resin composition and shaped articles thereof JSR Corporation (JP) 2002-07-17 EP disclosed