SCHEMBL200187

SCHEMBL200187

C1=CC2CC1CC2[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 1/20 0.33
RAB9A P51151 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
HIF1A Q16665 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
PTGS2 P35354 1/20 0.30
HRH1 P35367 1/20 0.30
KCNH2 Q12809 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296058 0.83 KDM4E (0.33) KDM4ETSHRKMT2A
SCHEMBL21525762 0.74 KDM4E (0.32) KDM4ETSHRALDH1A1KMT2ATDP1
SCHEMBL6701075 0.71 KDM4E (0.36) KDM4ETSHRALDH1A1KMT2ATDP1
SCHEMBL18560865 0.71 ALDH1A1 (0.32) KDM4ETSHRALDH1A1KMT2A
SCHEMBL11528508 0.70 KDM4E (0.36) KDM4ETSHRALDH1A1TDP1LMNA
SCHEMBL6750638 0.70 KDM4E (0.36) KDM4ETSHRALDH1A1KMT2ATDP1
SCHEMBL5425486 0.70 KMT2A (0.34) KDM4ETSHRALDH1A1KMT2A
SCHEMBL201969 0.70 ALDH1A1 (0.31) KDM4EALDH1A1KMT2ALMNA
SCHEMBL11527107 0.69 KDM4E (0.39) KDM4ETSHRALDH1A1KMT2ATDP1
SCHEMBL2605525 0.68 KDM4E (0.32) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
EP-1223195-B1 Thermoplastic resin composition and shaped articles thereof JSR CORP (JP) 2012-03-14 EP disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-6790914-B2 TRANSPARENT (CROSSLINKED) RESIN FILM CAN BE USED AS A POLARIZING FILM, SURFACE PROTECTIVE FILM, RETARDATION FILM, TRANSPARENT CONDUCTIVE FILM, LIGHT DIFFUSION FILM, FILM FOR AN EL DISPLAY DEVICE, TRANSPARENT CONDUCTIVE COMPOSITE MATERIAL, JSR CORPORATION (JP) 2004-09-14 US disclosed
US-20040106740-A1 Resin film and applications thereof JSR CORPORATION (JP) 2004-06-03 US disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed
US-6562908-B2 Blend of rubber reinforced thermoplastic resins, acrylic resins and thermoplastic norbornene resins; heat resistance, strength, processability, and laser marking properties JSR CORPORATION (JP) 2003-05-13 US disclosed
US-20020128392-A1 Thermoplastic resin composition and shaped articles thereof JSR CORPORATION (JP) 2002-09-12 US disclosed
EP-1223195-A2 Thermoplastic resin composition and shaped articles thereof JSR Corporation (JP) 2002-07-17 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed