Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455365 | 1.00 | CYP3A4 (0.42) | CYP3A4LMNACRHR1ALDH1A1DPP4 | |
| SCHEMBL28449266 | 0.87 | ABCB1 (0.37) | CYP3A4CRHR1ALDH1A1ABCB1HSP90AA1 | |
| SCHEMBL29607314 | 0.87 | CRHR1 (0.39) | CYP3A4LMNACRHR1ALDH1A1DPP4 | |
| SCHEMBL28460715 | 0.87 | CRHR1 (0.39) | CYP3A4LMNACRHR1ALDH1A1DPP4 | |
| SCHEMBL24397879 | 0.86 | CRHR1 (0.49) | CYP3A4CRHR1ALDH1A1HSP90AA1L3MBTL1 | |
| SCHEMBL28898753 | 0.85 | HSP90AA1 (0.33) | CYP3A4CRHR1ALDH1A1HSP90AA1KDM4E | |
| SCHEMBL24397796 | 0.84 | HPGD (0.48) | LMNAALDH1A1KDM4EGLAGAA | |
| SCHEMBL29606902 | 0.79 | ALDH1A1 (0.37) | CYP3A4LMNAALDH1A1KDM4EGLA | |
| SCHEMBL28898749 | 0.79 | ALDH1A1 (0.37) | CYP3A4LMNAALDH1A1KDM4EGLA | |
| SCHEMBL28459463 | 0.77 | HPGD (0.49) | LMNAALDH1A1POLBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |