Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | BLVRB | P30043 | 1/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60072 | 1.00 | MAOA (0.71) | MAOABLVRBHDAC6NPC1RAB9A | |
| SCHEMBL59154 | 0.92 | MAOA (0.78) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL29361641 | 0.83 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL29360108 | 0.83 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL29365205 | 0.83 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL60614 | 0.83 | MAOA (1.00) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL59167 | 0.82 | MAOA (0.97) | MAOABLVRBHDAC6NPC1RAB9A | |
| Ataluren SCHEMBL59165 | 0.82 | MAOA (0.97) | MAOABLVRBHDAC6NPC1RAB9A | |
| SCHEMBL60044 | 0.82 | MAOA (0.83) | MAOABLVRBHDAC6NPC1RAB9A | |
| SCHEMBL18507380 | 0.82 | RAB9A (0.63) | MAOABLVRBHDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889142-B1 | 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE | PTC THERAPEUTICS INC (US) | 2022-06-15 | — | — | EP | disclosed |