Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.63 |
| ▸ | NPC1 | O15118 | 11/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29606802 | 0.82 | MAOA (0.71) | RAB9ANPC1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL60072 | 0.82 | MAOA (0.71) | RAB9ANPC1SMN1; SMN2CASP3SENP7 | |
| SCHEMBL28642664 | 0.81 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL12895791 | 0.78 | TP53 (0.75) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL13882259 | 0.78 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL13427308 | 0.76 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL2604967 | 0.74 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL2604968 | 0.74 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL2604969 | 0.74 | NPC1 (0.64) | RAB9ANPC1SMN1; SMN2TP53CASP3 | |
| SCHEMBL13930832 | 0.73 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910551-B1 | 1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease | PTC THERAPEUTICS INC (US) | 2017-02-15 | — | — | EP | disclosed |