Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432831 | 1.00 | TDP1 (0.46) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL18188343 | 0.81 | TSHR (0.41) | TDP1ALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL8743905 | 0.79 | GPR35 (0.41) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL31202669 | 0.79 | GPR35 (0.41) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL898028 | 0.78 | ALDH1A1 (0.42) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL29745233 | 0.78 | ALDH1A1 (0.42) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL29004835 | 0.78 | ALDH1A1 (0.39) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL1749639 | 0.77 | TDP1 (0.44) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL56616 | 0.76 | MAPT (0.50) | TDP1ALDH1A1TSHRTXNRD1FGFR4 | |
| SCHEMBL29364858 | 0.76 | MAPT (0.50) | TDP1ALDH1A1TSHRTXNRD1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024226875-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR ATTENUATION OF MAMMALIAN TRANSLATION OF C-MYC OR N-MYC PROTEINS OF THE MYC PROTO-ONCOGENE FAMILY OF BHLH TRANSCRIPTION FACTORS | INITIAL THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |
| CN-118290350-A | Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders | 协同医药发展有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113631535-B | Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders | 协同医药发展有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116964055-A | Pesticidal tricyclic compounds | 巴斯夫欧洲公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-114437131-A | Iridium complex, nitrogen-containing tridentate ligand, and organic light-emitting diode | 季昀 | 2022-05-06 | — | — | CN | disclosed |