Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | BLK | P51451 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | STK3 | Q13188 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758134 | 1.00 | CHUK (0.44) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL28748440 | 1.00 | CHUK (0.44) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL7925295 | 0.93 | CYP1A2 (0.41) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL29101743 | 0.90 | SMPD1 (0.50) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL28041717 | 0.87 | ALDH1A1 (0.45) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL2851634 | 0.87 | ALDH1A1 (0.48) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL9710334 | 0.86 | THRA (0.48) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL9710151 | 0.86 | THRA (0.48) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL9850712 | 0.86 | THRA (0.48) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL8751862 | 0.86 | THRA (0.48) | CHUKDAPK3JAK2ROCK2PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437104-B | Compound containing benzothiophene condensed rings, preparation method and application thereof | 中国石油化工股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114437104-A | Compound containing benzothiophene fused ring and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | disclosed |