Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.48 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847862 | 1.00 | GAA (0.61) | GAATTBK1TTBK2ALDH1A1KDM4E | |
| SCHEMBL29426539 | 0.85 | GAA (0.66) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL3172089 | 0.85 | GAA (0.66) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL1403643 | 0.82 | GAA (0.72) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL861495 | 0.81 | PTPN2 (0.54) | GAATTBK1TTBK2ALDH1A1HSD17B10 | |
| SCHEMBL6168887 | 0.81 | GAA (0.66) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL7623605 | 0.81 | GAA (0.70) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL9705197 | 0.81 | GAA (0.65) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL10923552 | 0.81 | CA12 (0.46) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL31249571 | 0.81 | LMNA (0.54) | GAAALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539855-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Borah, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| EP-4351574-A1 | INHIBITORS OF TTBK1 | The General Hospital Corporation (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2023244775-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2022261627-A1 | INHIBITORS OF TTBK1 | THE GENERAL HOSPITAL CORPORATION (US) | 2022-12-15 | — | — | WO | disclosed |
| EP-3994142-A1 | CHEMICAL COMPOUNDS | Borah, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |