Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CFTR | P13569 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403643 | 0.86 | GAA (0.72) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL9705197 | 0.84 | GAA (0.65) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL7623605 | 0.84 | GAA (0.70) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL7529190 | 0.84 | KDM4E (0.66) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL2926607 | 0.84 | GAA (0.70) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL29400478 | 0.84 | GAA (0.70) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL9574892 | 0.83 | MAPT (0.56) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL1026723 | 0.83 | BRAF (0.56) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL268601 | 0.82 | CA12 (0.67) | GAAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL1321845 | 0.82 | GAA (0.62) | GAAALDH1A1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250312362-A1 | INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-10-09 | — | — | US | disclosed |
| EP-4525851-A1 | INHIBITORS OF MSBA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023224892-A1 | INHIBITORS OF MSBA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-11-23 | — | — | WO | disclosed |
| EP-1296540-B1 | DISPLAY | TORAY INDUSTRIES (JP) | 2019-10-16 | — | — | EP | disclosed |
| EP-1595870-B1 | PROCESS FOR PRODUCING PHENYLALANINE DERIVATIVE HAVING QUINAZOLINEDIONE SKELETON AND INTERMEDIATE FOR THE SAME | AJINOMOTO KK (JP) | 2015-09-23 | — | — | EP | disclosed |
| US-6887643-B2 | Photosensitive resin precursor composition | TORAY INDUSTRIES, INC. (JP) | 2005-05-03 | — | — | US | disclosed |
| EP-1509499-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2005-03-02 | — | — | EP | disclosed |
| US-20040053156-A1 | Photosensitive resin precursor composition | TORAY INDUSTRIES, INC. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6696112-B2 | POSITIVE-TYPE, PHOTOSENSITIVITY; FLAT PANEL DISPLAYS | TORAY INDUSTRIES, INC. (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-1388758-A1 | Photosensitive heat resistant resin precursor composition | TORAY INDUSTRIES, INC. (JP) | 2004-02-11 | — | — | EP | disclosed |
| WO-1998053361-A2 | POLARIZABLE AMINES AND POLYIMIDES FOR OPTICAL ALIGNMENT OF LIQUID CRYSTALS | ALLIANT TECHSYSTEMS INC. (US) | 1998-11-26 | — | — | WO | disclosed |
| US-5493011-A | PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS | HOECHST AG (DE) | 1996-02-20 | — | — | US | disclosed |
| US-4081439-A | Aromatic disazo pigments | CIBA-GEIGY CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4070353-A | FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4065449-A | Tetrachloro substituted disazo pigments | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-4053464-A | DISAZO PIGMENTS CONTAINING ETHER SUBSTITUTED ALKOXY CARBONYL GROUPS | CIBA-GEIGY CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-3988312-A | TETRAKISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3978038-A | POLYAMIDES, POLYESTERS, POLYURETHANES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3953496-A | ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250312362-A1 | INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MSRB3, ABCC1, MRPS34 | GAA 1230/4885ALDH1A1 4233/4885KDM4E 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.