Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14050066 | 1.00 | POLA1 (0.61) | POLA1MAPTPOLBGAASMN1; SMN2 | |
| SCHEMBL15305716 | 0.84 | RAB9A (0.55) | MAPTPOLBNPC1RAB9ANOD1 | |
| SCHEMBL20355745 | 0.84 | CYP1A2 (0.73) | MAPTPOLBNPC1RAB9ANOD1 | |
| SCHEMBL28736428 | 0.83 | NUDT1 (0.58) | MAPTPOLBNPC1RAB9ANOD1 | |
| SCHEMBL29609757 | 0.83 | NUDT1 (0.58) | MAPTPOLBNPC1RAB9ANOD1 | |
| SCHEMBL3233125 | 0.83 | MAPT (0.70) | POLA1MAPTPOLBGAASMN1; SMN2 | |
| SCHEMBL1320467 | 0.82 | KMT2A (0.66) | POLA1MAPTPOLBGAASMN1; SMN2 | |
| SCHEMBL28736243 | 0.81 | MAPT (0.72) | POLA1MAPTPOLBGAASMN1; SMN2 | |
| SCHEMBL29609310 | 0.81 | MAPT (0.72) | POLA1MAPTPOLBGAASMN1; SMN2 | |
| SCHEMBL16380596 | 0.79 | POLA1 (0.75) | POLA1MAPTPOLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191774-B | Heterocyclic compound, preparation method and application thereof | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |