Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.60 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153666 | 1.00 | PIN1 (0.60) | PIN1PDPK1KCNQ2PDE4APDE4B | |
| SCHEMBL14143104 | 1.00 | PIN1 (0.60) | PIN1PDPK1KCNQ2PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL27856372 | 0.98 | PIN1 (0.58) | PIN1PDPK1KCNQ2PDE4APDE4B | |
| SCHEMBL769134 | 0.90 | KMT2A (0.51) | PIN1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL29484101 | 0.90 | KMT2A (0.51) | PIN1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL29498272 | 0.86 | PIN1 (0.57) | PIN1PDPK1KCNQ2PDE4APDE4B | |
| SCHEMBL1898510 | 0.83 | PIN1 (0.54) | PIN1PDPK1KCNQ2IDO1 | |
| SCHEMBL3136218 | 0.82 | P2RX7 (0.46) | PIN1MEN1KMT2A | |
| SCHEMBL28937024 | 0.82 | PIN1 (0.56) | PIN1PDPK1KCNQ2PDE4APDE4B | |
| SCHEMBL4720088 | 0.82 | PIN1 (0.52) | PIN1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163752-A1 | HETEROCYCLIC COMPOUNDS AS PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-08-08 | — | — | WO | disclosed |
| CN-113905743-B | CD73 inhibitors and therapeutic uses thereof | 江苏恒瑞医药股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4251633-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115124878-A | Method for manufacturing rubber rain shoes with chameleon effect | 杭州星发彩印有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114644631-A | KRAS G12C protein mutation inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2022109741-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-06-02 | — | — | WO | disclosed |