Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769134 | 1.00 | KMT2A (0.51) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL29609016 | 0.90 | PIN1 (0.60) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL14143104 | 0.90 | PIN1 (0.60) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL1153666 | 0.90 | PIN1 (0.60) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| Hydrochloric Acid SCHEMBL27856372 | 0.89 | PIN1 (0.58) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL651410 | 0.87 | HTT (0.51) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL2115724 | 0.83 | ALDH1A1 (0.51) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL2529183 | 0.82 | LMNA (0.46) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL31262315 | 0.81 | HTT (0.49) | KMT2AMEN1TAS1R3TAS1R1PIN1 | |
| SCHEMBL2448483 | 0.81 | HTT (0.49) | KMT2AMEN1TAS1R3TAS1R1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251633-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022127827-A1 | KRASG12C PROTEIN MUTATION INHIBITOR AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 上海维申医药有限公司 | 2022-06-23 | — | — | WO | disclosed |
| CN-114644631-A | KRAS G12C protein mutation inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2022109741-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-06-02 | — | — | WO | disclosed |
| CN-112313234-B | Pyrazolo-triazolopyrimidine derivatives as A2A receptor antagonists | 百济神州有限公司 | 2022-04-29 | — | — | CN | disclosed |