Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propiomazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 2/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 6/20 | 1.00 |
| ▸ | HTR1A | P08908 | 6/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 6/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 6/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 6/20 | 1.00 |
| ▸ | DRD3 | P35462 | 6/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 6/20 | 1.00 |
| ▸ | DRD2 | P14416 | 3/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 2/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 2/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 2/20 | 1.00 |
| ▸ | HTR2A | P28223 | 2/20 | 1.00 |
| ▸ | HTR2C | P28335 | 2/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 1.00 |
| ▸ | HTR2B | P41595 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | MTOR | P42345 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)-Propiomazine SCHEMBL6910697 | 1.00 | CHRM2 (1.00) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL93770 | 1.00 | CHRM2 (1.00) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL29370554 | 1.00 | CHRM2 (1.00) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL30903904 | 0.99 | CHRM2 (0.98) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL141677 | 0.99 | CHRM2 (0.98) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL6372719 | 0.99 | CHRM2 (0.98) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL720224 | 0.98 | CHRM2 (0.96) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Propiomazine SCHEMBL3863991 | 0.94 | CHRM2 (0.88) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL10368273 | 0.88 | CHRM2 (0.79) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| Aceprometazine SCHEMBL142393 | 0.88 | HTR1A (0.79) | CHRM2HTR1ACHRM1ADRA1AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450967-A | System and method for playback of augmented reality content triggered by image recognition | 谷歌有限责任公司 | 2022-05-06 | — | — | CN | disclosed |