Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817975 | 1.00 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL6514206 | 1.00 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL6529748 | 1.00 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL24575927 | 0.88 | EPHX2 (0.64) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL2934798 | 0.86 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL1567110 | 0.86 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL8518963 | 0.86 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL7263715 | 0.86 | LMNA (0.61) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL5520593 | 0.85 | ALDH1A1 (0.63) | LMNAGAASSTR4EPHX2MEN1 | |
| SCHEMBL7868509 | 0.85 | LMNA (0.59) | LMNAGAASSTR4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524745-A | Preparation method of (R) -N-acetyl-alpha-arylethylamine derivative | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |