Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263715 | 1.00 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL8518963 | 1.00 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| Trifluoroacetic Acid SCHEMBL3338958 | 0.91 | HDAC3 (0.60) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL24575927 | 0.88 | EPHX2 (0.64) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL6529748 | 0.86 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL9817975 | 0.86 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL1567110 | 0.86 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL29609692 | 0.86 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL6514206 | 0.86 | LMNA (0.61) | LMNAGAAEPHX2SSTR4PDE2A | |
| SCHEMBL14484271 | 0.85 | LMNA (0.64) | LMNAGAAEPHX2PDE2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276230-A | Cyano-3-phenoxybenzyl N-1-(1-naphthyl) ethylcarbamate | ZOECON CORPORATION (US) | 1981-06-30 | — | — | US | claimed |
| US-20150038546-A1 | SUBSTITUTED CHROMAN COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2015-02-05 | — | — | US | disclosed |
| EP-2374802-B1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| EP-1836163-B1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-20100087427-A1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | BREITENSTEIN WERNER | 2010-04-08 | — | — | US | disclosed |
| EP-0038617-B1 | DIASTEREOMERS OF AMINO ACID ESTERS, PESTICIDAL COMPOSITIONS INCLUDING THEM AND METHOD OF CONTROLLING PESTS USING THEM | ZOECON CORPORATION (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0038617-A1 | Diastereomers of amino acid esters, pesticidal compositions including them and method of controlling pests using them | ZOECON CORPORATION (US) | 1981-10-28 | — | — | EP | disclosed |
| US-4276230-A | Cyano-3-phenoxybenzyl N-1-(1-naphthyl) ethylcarbamate | ZOECON CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4260633-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087427-A1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | REN, ACE, PEPD | LMNA 2796/4885GAA 84/4885EPHX2 1119/4885 |
| US-20150038546-A1 | SUBSTITUTED CHROMAN COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | CASR, RYR2, CALCR | LMNA 1922/4885GAA 1174/4885EPHX2 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.