SCHEMBL29610214

SCHEMBL29610214

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)NCC(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CALCR P30988 4/20 0.62
OPRM1 P35372 2/20 0.59
OPRD1 P41143 2/20 0.59
OPRK1 P41145 2/20 0.59
TFPI P10646 3/20 0.57
CALCRL Q16602 1/20 0.56
NPY2R P49146 4/20 0.56
NPY4R P50391 4/20 0.56
NPY5R Q15761 4/20 0.56
NPY1R P25929 3/20 0.56
KEAP1 Q14145 1/20 0.56
CXCR4 P61073 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29988048 0.90 NPY2R (0.64) CALCRTFPINPY2RNPY4RNPY5R
SCHEMBL30176437 0.90 TFPI (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30176414 0.90 TFPI (0.64) TFPINPY2RNPY4RNPY5RNPY1R
SCHEMBL30073900 0.89 CALCR (0.66) CALCROPRM1OPRD1OPRK1TFPI
SCHEMBL29949429 0.88 TFPI (0.62) CALCROPRM1OPRD1OPRK1TFPI
SCHEMBL29949393 0.88 CALCRL (0.59) CALCROPRM1OPRD1OPRK1CALCRL
SCHEMBL31182463 0.88 CALCR (0.60) CALCRCALCRLNPY2RNPY4RNPY5R
SCHEMBL30824299 0.88 CALCR (0.61) CALCROPRM1OPRD1OPRK1TFPI
SCHEMBL29655865 0.88 OPRD1 (0.61) CALCROPRM1OPRD1OPRK1
SCHEMBL30906484 0.88 TFPI (0.59) CALCROPRM1OPRD1OPRK1TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294433-A1 IMMUNOGENIC COMPOSITION, USE AND METHODS GlaxoSmithKline Biologicals SA (BE) 2023-12-27 EP disclosed
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 US disclosed
WO-2022175423-A1 IMMUNOGENIC COMPOSITION, USE AND METHODS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-08-25 WO disclosed
EP-4009951-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GlaxoSmithKline Biologicals S.A. (BE) 2022-06-15 EP disclosed
EP-4010014-A1 IMMUNOGENIC COMPOSITION GlaxoSmithKline Biologicals S.A. (BE) 2022-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 CALCR 415/4885OPRM1 3724/4885OPRD1 969/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 CALCR 415/4885OPRM1 3724/4885OPRD1 969/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 CALCR 1308/4885OPRM1 2604/4885OPRD1 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.