Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20265949 | 0.84 | THRB (0.34) | POLBESR2 | |
| SCHEMBL30124141 | 0.73 | BRD4 (0.40) | HPGD | |
| SCHEMBL5008374 | 0.71 | CYSLTR2 (0.34) | — | |
| SCHEMBL10366459 | 0.70 | HRH3 (0.44) | GRM2POLBESR2 | |
| SCHEMBL12602022 | 0.70 | POLB (0.59) | POLBESR2ALOX5HPGD | |
| SCHEMBL8510380 | 0.68 | CA2 (0.50) | — | |
| SCHEMBL9532685 | 0.67 | POLB (0.38) | GRM2POLBESR2ALOX5HPGD | |
| SCHEMBL31619269 | 0.67 | TRPA1 (0.34) | — | |
| SCHEMBL30236022 | 0.67 | CYP2A6 (0.36) | — | |
| SCHEMBL29489983 | 0.66 | PDGFRB (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080576-A1 | COMPOSITION COMPRISING PMCA INHIBITOR FOR TREATMENT OF CORONAVIRUS INFECTION OR INFECTIOUS DISEASES | 김홍렬 | 2022-04-21 | — | — | WO | disclosed |