SCHEMBL29610258

SCHEMBL29610258

CC(C)C(N)C(=O)OOC(=O)[C@H](N)CCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRE P78334 2/20 0.50
GABRA6 Q16445 2/20 0.50
GABRG1 Q8N1C3 2/20 0.50
GABRG3 Q99928 2/20 0.50
GABRQ Q9UN88 2/20 0.50
CYP1A2 P05177 2/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997572 0.87 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL537128 0.87 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29564893 0.84 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29409622 0.81 BLM (0.57) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28805252 0.78 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4537589 0.77 GABRP (0.54) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7780572 0.77 GABRP (0.54) GABRPGABRDGABRA1GABRB1GABRG2
D-Glutamate SCHEMBL109452 0.77 CYP1A2 (0.72) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2785568 0.77 SLC7A5 (0.55) GABRPGABRDGABRA1GABRB1GABRG2
Glutamic Acid SCHEMBL109453 0.77 CYP1A2 (0.72) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 US disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 US disclosed
US-12070506-B2 Steroids and antibody-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2024-08-27 US disclosed
US-20240247030-A1 TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES JPMORGAN CHASE BANK, N.A. 2024-07-25 US disclosed
WO-2024125641-A1 SERIES OF POLYPEPTIDES/PROTEINS AND USES THEREOF 陈敏 2024-06-20 WO disclosed
EP-3900742-B1 TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES SEAGEN INC (US) 2024-05-15 EP disclosed
US-20220281957-A1 MODIFIED HUMAN VARIABLE DOMAINS MERUS N.V. (NL) 2022-09-08 US disclosed
EP-4010364-A1 MODIFIED HUMAN VARIABLE DOMAINS Merus N.V. (NL) 2022-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 GABRP 1228/4885GABRD 669/4885GABRA1 1005/4885
US-12070506-B2 Steroids and antibody-conjugates thereof SERPINA6, NR3C1, NR3C2 GABRP 1228/4885GABRD 669/4885GABRA1 1005/4885
US-20240247030-A1 TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES CD47, CD44, MSR1 GABRP 2855/4885GABRD 2661/4885GABRA1 2532/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 GABRP 1228/4885GABRD 669/4885GABRA1 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.