Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 5/20 | 0.59 |
| ▸ | FGF2 | P09038 | 2/20 | 0.59 |
| ▸ | HPSE | Q9Y251 | 9/20 | 0.58 |
| ▸ | SERPINC1 | P01008 | 2/20 | 0.55 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960806 | 1.00 | FGF1 (0.59) | FGF1FGF2HPSESERPINC1F10 | |
| SCHEMBL16316512 | 0.96 | FGF1 (0.55) | FGF1FGF2HPSESERPINC1F10 | |
| SCHEMBL16316488 | 0.94 | FGF1 (0.64) | FGF1FGF2HPSESERPINC1F10 | |
| SCHEMBL4902478 | 0.88 | FGF1 (0.59) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL4895055 | 0.88 | FGF1 (0.59) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL14020079 | 0.88 | FGF1 (0.59) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL4180806 | 0.87 | FGF1 (0.69) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL4906384 | 0.84 | FGF1 (0.70) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL14020073 | 0.84 | FGF1 (0.70) | FGF1FGF2HPSESERPINC1 | |
| SCHEMBL4904646 | 0.84 | FGF1 (0.70) | FGF1FGF2HPSESERPINC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754250-B2 | Composition and methods for treating Alzheimer's disease and other amyloidoses | PROTEOTECH, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080206162-A1 | Composition and Methods for Treating Alzheimer's Disease and Other Amyloidoses | UNIVERSITY OF WASHINGTON | 2008-08-28 | — | — | US | disclosed |
| US-7371731-B2 | Methods for using glucose pentasulfate for treating amyloid associated with type II diabetes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-05-13 | — | — | US | disclosed |
| EP-1019044-B1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2007-04-11 | — | — | EP | disclosed |
| US-7029710-B2 | Methods of isolation of amyloid inhibitory ingredients within Uncaria tomentosa | UNIVERSITY OF WASHINGTON (US) | 2006-04-18 | — | — | US | disclosed |
| US-6939570-B1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON (US) | 2005-09-06 | — | — | US | disclosed |
| US-20040229824-A1 | Methods for using specific saccharides for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-18 | — | — | US | disclosed |
| US-6767898-B2 | Methods for using specific saccharides for treating alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON | 2004-07-27 | — | — | US | disclosed |
| US-20040086585-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-06 | — | — | US | disclosed |
| US-20040076698-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-22 | — | — | US | disclosed |
| US-20010055630-A1 | Compostion and methods for treating alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-12-27 | — | — | US | disclosed |
| US-6264994-B1 | Compositions for treating alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON | 2001-07-24 | — | — | US | disclosed |
| EP-1014996-A4 | SPECIFIC SACCHARIDE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2000-10-11 | — | — | EP | disclosed |
| EP-1019044-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | University of Washington (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-1014996-A1 | SPECIFIC SACCHARIDE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | THE UNIVERSITY OF WASHINGTON (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000033659-A1 | COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIVERSITY OF WASHINGTON (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000030666-A1 | COMPOSITION AND METHODS FOR INHIBITING THE FORMATION OF BRAIN AMYLOID DEPOSITS | UNIVERSITY OF WASHINGTON (US) | 2000-06-02 | — | — | WO | disclosed |
| US-6037327-A | Specific saccharide compositions and methods for treating Alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON (US) | 2000-03-14 | — | — | US | disclosed |
| WO-1999009999-A1 | SPECIFIC SACCHARIDE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIVERSITY OF WASHINGTON (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1998051302-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIVERSITY OF WASHINGTON (US) | 1998-11-19 | — | — | WO | disclosed |