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SCHEMBL4902478

SCHEMBL4902478

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nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 8/20 0.59
▸ FGF2 P09038 6/20 0.59
▸ SERPINC1 P01008 1/20 0.47
▸ HPSE Q9Y251 14/20 0.45
▸ VEGFA P15692 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4895055 1.00 FGF1 (0.59) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14020079 1.00 FGF1 (0.59) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL4899810 0.94 FGF1 (0.64) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14020074 0.94 FGF1 (0.64) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14020078 0.94 FGF1 (0.64) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14020081 0.94 FGF1 (0.64) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL16316512 0.93 FGF1 (0.55) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14020080 0.91 FGF1 (0.51) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL4906384 0.88 FGF1 (0.70) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL2961028 0.88 FGF1 (0.59) FGF1FGF2SERPINC1HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080249165-A1 Glycosides and Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2008-10-09 — — US claimed
US-20080249165-A1 Glycosides and Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2008-10-09 — — US disclosed
WO-2006017727-A2 GLYCOSIDES AND SALTS THEREOF IVAX CORPORATION (US) 2006-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249165-A1 Glycosides and Salts Thereof AREG, MRGPRX2, IL33 FGF1 540/4885FGF2 799/4885SERPINC1 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.