Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239578 | 0.92 | TSHR (0.40) | TSHRFDPSLPAR3LPAR2S1PR2 | |
| SCHEMBL2961044 | 0.81 | FDPS (0.37) | TSHRFDPSLPAR3LPAR2S1PR2 | |
| SCHEMBL2963056 | 0.75 | TSHR (0.41) | TSHRFDPSLPAR3LPAR2ALDH1A1 | |
| SCHEMBL2952200 | 0.74 | LPAR2 (0.35) | TSHRLPAR3LPAR2 | |
| SCHEMBL13239580 | 0.72 | FDPS (0.57) | TSHRFDPSLPAR3LPAR2S1PR2 | |
| Diethyl Hydrogen Phosphate SCHEMBL28293408 | 0.70 | TSHR (0.57) | TSHRLPAR3LPAR2ALDH1A1 | |
| SCHEMBL8993904 | 0.70 | LPAR3 (0.47) | TSHRLPAR3LPAR2ALDH1A1 | |
| SCHEMBL9701750 | 0.70 | LPAR3 (0.47) | TSHRLPAR3LPAR2ALDH1A1 | |
| SCHEMBL2955740 | 0.70 | LPAR3 (0.47) | TSHRLPAR3LPAR2ALDH1A1 | |
| SCHEMBL13334729 | 0.69 | FDPS (0.52) | TSHRFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060280719-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280719-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC43A1 | TSHR 76/4885FDPS 1734/4885LPAR3 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.