Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952206 | 0.76 | LPAR3 (0.36) | LPAR2LPAR3 | |
| SCHEMBL2961043 | 0.74 | TSHR (0.42) | LPAR2LPAR3TSHR | |
| SCHEMBL2960477 | 0.73 | LPAR3 (0.36) | LPAR2LPAR3TSHR | |
| SCHEMBL13239578 | 0.72 | TSHR (0.40) | LPAR2LPAR3TSHR | |
| SCHEMBL2955740 | 0.70 | LPAR3 (0.47) | LPAR2LPAR3TSHR | |
| SCHEMBL9701750 | 0.70 | LPAR3 (0.47) | LPAR2LPAR3TSHR | |
| SCHEMBL8993904 | 0.70 | LPAR3 (0.47) | LPAR2LPAR3TSHR | |
| SCHEMBL2961044 | 0.69 | FDPS (0.37) | LPAR2LPAR3TSHR | |
| SCHEMBL1219734 | 0.68 | PPARD (0.47) | LPAR2LPAR3TSHR | |
| SCHEMBL9701979 | 0.67 | LPAR3 (0.44) | LPAR2LPAR3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060280719-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280719-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC43A1 | LPAR2 1433/4885LPAR3 1651/4885TSHR 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.